Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
EN | CN

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-JAK/STAT Signaling-STAT-LLL3
LLL3

Chemical Structure : LLL3

CAS No.: 63972-38-3

Add to Favorites

LLL3 (STAT3 inhibitor LLL3)

Catalog No.: PC-61660Not For Human Use, Lab Use Only.

LLL3 is a structural analogue of STA-21 that acts as a novel STAT3 inhibitor, inhibits STAT3-dependent transcriptional and DNA binding activities.

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote
250 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    LLL3 is a structural analogue of STA-21 that acts as a novel STAT3 inhibitor, inhibits STAT3-dependent transcriptional and DNA binding activities.
    LLL3 also inhibits viability of U87, U373, and U251 glioblastoma cells as well as induces apoptosis of these glioblastoma cell lines.
    LLL3 exhibits prolonged survival in U87 glioblastoma tumour-bearing mice.

    Physicochemical Properties

    M.Wt 266.252
    Formula C16H10O4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    1-acetyl-5-hydroxyanthracene-9,10-dione

    References

    1. Fuh B, et al. Br J Cancer. 2009 Jan 13;100(1):106-12.

    2. Fossey SL, et al. BMC Cancer. 2009 Mar 10;9:81.

    3. Mencalha AL, et al. Cancer Chemother Pharmacol. 2010 May;65(6):1039-46.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: