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Chemical Structure : LMP517
Catalog No.: PC-72441Not For Human Use, Lab Use Only.
LMP517 (NSC 781517) is a non-camptothecin, dual TOP1 and TOP2 topoisomerase inhibitor.
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LMP517 (NSC 781517) is a non-camptothecin, dual TOP1 and TOP2 topoisomerase inhibitor.
LMP517 showed better antitumor activity than its parent compound LMP744 against H82 (small cell lung cancer) xenografts.
| M.Wt | 410.401 | |
| Formula | C22H19FN2O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Laetitia Marzi, et al. Mol Cancer Ther. 2020 Aug;19(8):1589-1597.
2. Marzi L, et al. Mol Cancer Ther. 2018 Aug;17(8):1694-1704.
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