LMP744 | TOP1 inhibitor | Probechem Biochemicals

Chemical Structure : LMP744

Catalog No.: PC-72442Not For Human Use, Lab Use Only.

LMP744 (MJ-III-65, NSC706744) is a small molecule TOP1 inhibitor antitumoral activity.

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Biological Activity

LMP744 (MJ-III-65, NSC706744) is a small molecule Topoisomerase I (Top1) inhibitor antitumoral activity.

M.Wt	452.463
Formula	C24H24N2O7
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	6-(3-((2-hydroxyethyl)amino)propyl)-2,3-dimethoxy-5H-[1,3]dioxolo[4',5':5,6]indeno[1,2-c]isoquinoline-5,12(6H)-dione

1. Laetitia Marzi, et al. Mol Cancer Ther. 2020 Aug;19(8):1589-1597.

2. Marzi L, et al. Mol Cancer Ther. 2018 Aug;17(8):1694-1704.