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LP-922056

Chemical Structure : LP-922056

CAS No.: 1365060-22-5

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LP-922056 (LP922056)

Catalog No.: PC-72826Not For Human Use, Lab Use Only.

LP-922056 (LP922056) is a potent Notum inhibitor with IC50 of 1.1 nM in OPTS assays.

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10 mg $88 In stock
25 mg $148 In stock
50 mg $238 In stock
100 mg $388 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

LP-922056 (LP922056) is a potent Notum inhibitor with IC50 of 1.1 nM in OPTS assays.
LP-922056 is a valuable chemical tool for exploring the role of Notum in Wnt signaling at a cellular level and for use in animal disease models.

Physicochemical Properties

M.Wt 300.775
Formula C11H9ClN2O2S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-((6-Chloro-7-cyclopropylthieno[3,2-d]pyrimidin-4-yl)thio)acetic acid

References

1. Elliott D Bayle, et al. J Med Chem. 2021 Apr 22;64(8):4289-4311.

2. Zhao Y, et al. Future Med Chem. 2021 Jun;13(11):1001-1015.

3. James E Tarver Jr, et al. Bioorg Med Chem Lett. 2016 Mar 15;26(6):1525-1528.

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