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LP-935001

Chemical Structure : LP-935001

CAS No.: 1875037-24-3

LP-935001 (LP935001)

Catalog No.: PC-49793Not For Human Use, Lab Use Only.

LP-935001 (LP935001) is a potent, selective and orally-active NOTUM with enzyme IC50 of 0.4 nM for both of human and mouse Notum.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

LP-935001 (LP935001) is a potent, selective and orally-active NOTUM with enzyme IC50 of 0.4 nM for both of human and mouse Notum.

Physicochemical Properties

M.Wt 282.71
Formula C13H8ClFO2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-chloro-8-fluoro-4,5-dihydronaphtho[1,2-b]thiophene-2-carboxylic acid

References

1. Robert Brommage, et al. Bone Res. 2019 Jan 8;7:2.

2. Han Q, et al. Bioorg. Med. Chem. Lett. 26, 1184–1187 (2016).

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