LPA1 antagonist HL001 | LPA1 antagonist

Chemical Structure : LPA1 antagonist HL001

LPA1 antagonist HL001 (HL001)

Catalog No.: PC-21569Not For Human Use, Lab Use Only.

HL001 is a novel lysophosphatidic acid 1 (LPA1) receptor antagonist, suppresses fibrosis-associated subpopulations of fibroblasts, exhibits significant anti-fibrotic effects both in murine models and human organoid models.

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Biological Activity

HL001 is a novel lysophosphatidic acid 1 (LPA1) receptor antagonist, suppresses fibrosis-associated subpopulations of fibroblasts, exhibits significant anti-fibrotic effects both in murine models and human organoid models.

Physicochemical Properties

M.Wt	548.05
Formula	C30H26ClNO5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-1-(4'-(5-chloro-3-(((1-phenylethoxy)carbonyl)amino)thiophen-2-yl)-2'-methoxy-[1,1'-biphenyl]-4-yl)cyclopropane-1-carboxylic acid

References

1. Yuki Yamamoto, et al. European Respiratory Journal 2023 62: OA898.

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LPA1 antagonist HL001 (HL001)

Biological Activity

Physicochemical Properties

References

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