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LPM3480226

Chemical Structure : LPM3480226

CAS No.: 2101916-81-6

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LPM3480226 (LY-01013)

Catalog No.: PC-49662Not For Human Use, Lab Use Only.

LPM3480226 (LY-01013) is a potent, selective IDO1/TDO dual inhibitor, inhibits the initial and rate-limiting enzymes in tryptophan metabolism, which play an essential role in mediating immunosuppression in tumor microenvironment.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    LPM3480226 (LY-01013) is a potent, selective IDO1/TDO dual inhibitor, inhibits the initial and rate-limiting enzymes in tryptophan metabolism, which play an essential role in mediating immunosuppression in tumor microenvironment.

    Physicochemical Properties

    M.Wt 419.23
    Formula C12H12BrFN6O3S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (E)-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-((2-ureidoethyl)thio)-1,2,5-oxadiazole-3-carboximidamide

    References

    1. Patent  WO2018024208 A1.

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