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LPM3480226

Chemical Structure : LPM3480226

CAS No.: 2101916-81-6

LPM3480226 (LY-01013)

Catalog No.: PC-49662Not For Human Use, Lab Use Only.

LPM3480226 (LY-01013) is a potent, selective IDO1/TDO dual inhibitor, inhibits the initial and rate-limiting enzymes in tryptophan metabolism, which play an essential role in mediating immunosuppression in tumor microenvironment.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

LPM3480226 (LY-01013) is a potent, selective IDO1/TDO dual inhibitor, inhibits the initial and rate-limiting enzymes in tryptophan metabolism, which play an essential role in mediating immunosuppression in tumor microenvironment.

Physicochemical Properties

M.Wt 419.23
Formula C12H12BrFN6O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-((2-ureidoethyl)thio)-1,2,5-oxadiazole-3-carboximidamide

References

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