LPM3480226 (LY-01013)

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Chemical Structure : LPM3480226

Catalog No.: PC-49662Not For Human Use, Lab Use Only.

LPM3480226 (LY-01013) is a potent, selective IDO1/TDO dual inhibitor, inhibits the initial and rate-limiting enzymes in tryptophan metabolism, which play an essential role in mediating immunosuppression in tumor microenvironment.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

LPM3480226 (LY-01013) is a potent, selective IDO1/TDO dual inhibitor, inhibits the initial and rate-limiting enzymes in tryptophan metabolism, which play an essential role in mediating immunosuppression in tumor microenvironment.

Physicochemical Properties

M.Wt	419.23
Formula	C12H12BrFN6O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-((2-ureidoethyl)thio)-1,2,5-oxadiazole-3-carboximidamide

References

1. Patent WO2018024208 A1.

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