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LPXC-516

Chemical Structure : LPXC-516

CAS No.: 2170600-27-6

LPXC-516 (LPXC516)

Catalog No.: PC-38312Not For Human Use, Lab Use Only.

LPXC-516 is a potent bacterial LpxC inhibitor with IC50 of 0.68 nM (P. aeruginosa LpxC), shows potency against the P. aeruginosa isolates with MIC90 of 2 ug/mL.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

LPXC-516 is a potent bacterial LpxC inhibitor with IC50 of 0.68 nM (P. aeruginosa LpxC), shows potency against the P. aeruginosa isolates with MIC90 of 2 ug/mL.

Physicochemical Properties

M.Wt 420.436
Formula C19H20N2O7S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-N-(2-(hydroxyamino)-1-(3-methoxy-1,1-dioxidothietan-3-yl)-2-oxoethyl)-4-(6-hydroxyhexa-1,3-diyn-1-yl)benzamide

References

1. Krause KM, et al. Antimicrob Agents Chemother. 2019 Oct 22;63(11):e00977-19. 

2. Cohen F, et al. ChemMedChem. 2019 Aug 20;14(16):1560-1572.

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