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Chemical Structure : LQFM215
Catalog No.: PC-21191Not For Human Use, Lab Use Only.
LQFM215 (LQFM-215) is a synthetic L-proline transporter (PROT/SLC6A7) inhibitor, inhibits proline uptake in hippocampal synaptosome with IC50 of 20.4 uM, present neuroprotective potential.
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LQFM215 (LQFM-215) is a synthetic L-proline transporter (PROT/SLC6A7) inhibitor, inhibits proline uptake in hippocampal synaptosome with IC50 of 20.4 uM, present neuroprotective potential.
LQFM215 (10.0 mg/kg) reduces animal motility, without inducing anxious, depressive behaviors, or cognitive impairments, evaluated in the open-field test in mice.
LQFM215 (10.0 mg/kg) prevents an increase in infarction area and motor impairments in the MCAO model, reduces infarction area and motor impairments in the MCAO model.
| M.Wt | 394.56 | |
| Formula | C25H34N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Carvalho GA, et al. Pharmacol Rep. 2023 Apr;75(2):276-292.
2. Carvalho GA, et al. Neurochem Res. 2023 Sep 9. doi: 10.1007/s11064-023-04018-3.
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