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Chemical Structure : LSN3172176
Catalog No.: PC-63443Not For Human Use, Lab Use Only.
LSN3172176 is a potent, selectiive M1 mAChR partial agonist (EC50 2.4-7.0nM, Emax 43%-73%), shows binding selectivity for M1 mAChRs (Kd=1.5 nM).
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LSN3172176 is a potent, selectiive M1 mAChR partial agonist (EC50 2.4-7.0nM, Emax 43%-73%), shows binding selectivity for M1 mAChRs (Kd=1.5 nM).
LSN3172176 is a potential PET tracer for assessment of M1 mAChR target engagement in the clinic and to further elucidate the function of M1 mAChRs in health and disease.
| M.Wt | 385.508 | |
| Formula | C22H31N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Mogg AJ, et al. J Pharmacol Exp Ther. 2018 Apr 11. pii: jpet.117.246454.
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