Chemical Structure : LXR-623
CAS No.:
875787-07-8
LXR-623
(WAY-252623;LXR623;LXR 623;WAY252623;WAY 252623)
Catalog No. : PC-42687Not For Human Use, Lab Use Only.
LXR-623 (WAY 252623) is a clinically viable, highly brain-penetrant LXRα-partial/LXRβ-full agonist with binding Ki of 33 nM/248 nM, respectively.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4268701
Biological Activity
LXR-623 (WAY 252623) is a clinically viable, highly brain-penetrant LXRα -partial/LXRβ -full agonist with binding Ki of 33 nM/248 nM, respectively.
Physicochemical Properties
M.Wt
422.7784
Formula
C21H12ClF5N2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 47 mg/mL
Chemical Name/SMILES
2H-Indazole, 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-
References
1. Wrobel J, et al. J Med Chem.
2. DiBlasio-Smith EA, et al. J Transl Med.
3. Villa GR, et al. Cancer Cell.
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