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Chemical Structure : LY-83583
CAS No.: 91300-60-6
Catalog No.: PC-62156Not For Human Use, Lab Use Only.
LY-83583 (LY83583) is an inhibitor of soluble guanylate cyclase (sGC) and of cGMP production, inhibits sGC in human platelets with IC50 of 2 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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LY-83583 (LY83583) is an inhibitor of soluble guanylate cyclase (sGC) and of cGMP production, inhibits sGC in human platelets with IC50 of 2 uM.
LY-83583 also inhibits leukotriene synthesis in guinea pig lung and rat peritoneal cells with an IC50 value of 1.8 uM.
LY-83583 is a noncompetitive inhibitor of glutathione reductase in bovine intestinal mucosa with Ki of 3 uM.
| M.Wt | 250.3 | |
| Formula | C15H10N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
6-(phenylamino)-5,8-quinolinedione |
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1. Butcher RA, et al. Nat Chem Biol. 2006 Feb;2(2):103-9.
2. Mülsch A, et al. Naunyn Schmiedebergs Arch Pharmacol. 1989 Jul;340(1):119-25.
3. Fleisch JH, et al. J Pharmacol Exp Ther. 1984 Jun;229(3):681-9.
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