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LY2452473

Chemical Structure : LY2452473

CAS No.: 1029692-15-6

LY2452473 (TT 701, OPK 88004, LY-2452473)

Catalog No.: PC-61999Not For Human Use, Lab Use Only.

LY2452473 (TT 701, OPK 88004) is an orally bioavailable selective androgen receptor modulator (SARM) being developed for the treatment of disorders related to hypogonadism.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

LY2452473 (TT 701, OPK 88004) is an orally bioavailable selective androgen receptor modulator (SARM) being developed for the treatment of disorders related to hypogonadism.
LY2452473 has the potential advantage of eliciting androgen receptor specificity and tissue selectivity to produce the beneficial effects of testosterone on bone, muscle, and improvements in erectile function over a PDE5i alone, with minimal steroid-related adverse effects.

Physicochemical Properties

M.Wt 374.444
Formula C22H22N4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Isopropyl N-[(2S)-7-cyano-4-(2-pyridylmethyl)-2,3-dihydro-1H-cyclopenta[b]indol-2-yl]carbamate

References

1. Yi P, et al. Drug Metab Dispos. 2012 Dec;40(12):2354-64.

2. Noey EL, et al. J Org Chem. 2017 Jun 2;82(11):5904-5909.

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