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Chemical Structure : LY255283
CAS No.: 117690-79-6
Catalog No.: PC-21589Not For Human Use, Lab Use Only.
LY255283 is a selective, competitive antagonist of leukotriene B4 receptor (BLT2) with IC50 of 1 uM, 10-fold selective over BLT1 receptor.
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|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $198 | In stock | |
| 25 mg | $298 | In stock | |
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LY255283 is a selective, competitive antagonist of leukotriene B4 receptor (BLT2) with IC50 of 1 uM, 10-fold selective over BLT1 receptor.
LY255283 inhibits LTB4-induced contraction of lung parenchyma (pA2 = 7.2).
LY255283 reduces LTB4-mediated airway obstruction in guinea pigs following i.v. and oral administration.
| M.Wt | 360.46 | |
| Formula | C19H28N4O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1-[5-Ethyl-2-hydroxy-4-[[6-methyl-6-(1H-tetrazol-5-yl)heptyl]oxy]phenyl]ethanone |
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1. D K Herron, et al. J Med Chem. 1992 May 15;35(10):1818-28.
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