Globalagliatin (LY2608204) | Glucokinase activator

Chemical Structure : LY2608204

CAS No.: 1234703-40-2

LY2608204 (Globalagliatin, LY-2608204)

Catalog No.: PC-49836Not For Human Use, Lab Use Only.

Globalagliatin (LY2608204) is a potent, small molecule activator of glucokinase (GK) with EC50 value of 42 nM.

Packing	Price	Stock
5 mg	$128	In stock
10 mg	$198	In stock
25 mg	$348	In stock
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Biological Activity

Globalagliatin (LY2608204) is a potent, small molecule activator of glucokinase (GK) with EC50 value of 42 nM.
Globalagliatin (LY2608204) induces glucose metabolism and reduces glucose levels for the treatment of type 2 diabetes.

Physicochemical Properties

M.Wt	559.80
Formula	C28H37N3O3S3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(1R,2S)-2-Cyclohexyl-1-[4-(cyclopropylsulfonyl)phenyl]-N-[5-[[2-(1-pyrrolidinyl)ethyl]thio]-2-thiazolyl]cyclopropanecarboxamide

References

1. Zheng S, et al. Clin Drug Investig. 2020 Dec;40(12):1155-1166

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LY2608204 (Globalagliatin, LY-2608204)

Biological Activity

Physicochemical Properties

References

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