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LY2608204

Chemical Structure : LY2608204

CAS No.: 1234703-40-2

LY2608204 (Globalagliatin)

Catalog No.: PC-49836Not For Human Use, Lab Use Only.

Globalagliatin (LY2608204) is a potent, small molecule activator of glucokinase (GK) with EC50 value of 42 nM, induces glucose metabolism and reduces glucose levels for the treatment of type 2 diabetes.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Globalagliatin (LY2608204) is a potent, small molecule activator of glucokinase (GK) with EC50 value of 42 nM, induces glucose metabolism and reduces glucose levels for the treatment of type 2 diabetes.

Physicochemical Properties

M.Wt 559.80
Formula C28H37N3O3S3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(1R,2S)-2-Cyclohexyl-1-[4-(cyclopropylsulfonyl)phenyl]-N-[5-[[2-(1-pyrrolidinyl)ethyl]thio]-2-thiazolyl]cyclopropanecarboxamide

References

1. Zheng S, et al. Clin Drug Investig. 2020 Dec;40(12):1155-1166

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