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Chemical Structure : LY3104607
Catalog No.: PC-60235Not For Human Use, Lab Use Only.
LY3104607 (LY-3104607) is a potent, selective, orally available GPR40 agonist with Ki of 15 nM, β-arrestin EC50 of 108 nM.
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LY3104607 (LY-3104607) is a potent, selective, orally available GPR40 agonist with Ki of 15 nM, β-arrestin EC50 of 108 nM.
LY3104607 demonstrates functional potency and glucose dependent insulin secretion in primary islets from rats.
LY3104607 dose-dependently reduces glucose levels in vivo.
| M.Wt | 439.515 | |
| Formula | C27H25N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Hamdouchi C, et al. J Med Chem. 2017 Dec 13. doi: 10.1021/acs.jmedchem.7b01411.
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