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Chemical Structure : LY450108
CAS No.: 376594-67-1
Catalog No.: PC-42745Not For Human Use, Lab Use Only.
A potent, selective, and centrally active positive allosteric modulator of AMPAR-mediated neurotransmission, which increase ion channel flux in the presence of agonist by suppressing desensitization and/or deactivation of the receptors..
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $290.4 | In stock | |
| 50 mg | $844.8 | In stock |
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A potent, selective, and centrally active positive allosteric modulator of AMPAR-mediated neurotransmission, which increase ion channel flux in the presence of agonist by suppressing desensitization and/or deactivation of the receptors.
| M.Wt | 396.4514 | |
| Formula | C19H22F2N2O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Benzamide, 3,5-difluoro-N-[4-[(1R)-1-methyl-2-[[(1-methylethyl)sulfonyl]amino]ethyl]phenyl]- |
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1. O'Neill MJ, et al. Curr Drug Targets. 2007 May;8(5):603-20.
2. Jhee SS, et al. J Clin Pharmacol. 2006 Apr;46(4):424-32.
3. O'Neill MJ, et al. Curr Drug Targets CNS Neurol Disord. 2004 Jun;3(3):181-94.
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