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Chemical Structure : LY451395
CAS No.: 375345-95-2
Catalog No.: PC-42744Not For Human Use, Lab Use Only.
A potent, selective, and centrally active positive allosteric modulator of AMPAR-mediated neurotransmission, which increase ion channel flux in the presence of agonist by suppressing desensitization and/or deactivation of the receptors..
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $400 | In stock | |
| 50 mg | $1200 | In stock | |
| 100 mg | $1680 | In stock |
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A potent, selective, and centrally active positive allosteric modulator of AMPAR-mediated neurotransmission, which increase ion channel flux in the presence of agonist by suppressing desensitization and/or deactivation of the receptors.
| M.Wt | 438.6039 | |
| Formula | C21H30N2O4S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-Propanesulfonamide, N-[(2R)-2-[4'-[2-[(methylsulfonyl)amino]ethyl][1,1'-biphenyl]-4-yl]propyl]- |
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1. O'Neill MJ, et al. Curr Drug Targets CNS Neurol Disord. 2004 Jun;3(3):181-94.
2. Zmijewski M, et al. Drug Metab Dispos. 2006 Jun;34(6):925-31.
3. Malá H, et al. Behav Brain Res. 2012 Jan 1;226(1):18-25.
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