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Chemical Structure : LYS228
Catalog No.: PC-63351Not For Human Use, Lab Use Only.
LYS228 is a novel potent monobactam that shows potent activity against carbapenem-resistant isolates of Enterobacteriaceae with MIC90 of 2 ug/ml.
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LYS228 is a novel potent monobactam that shows potent activity against carbapenem-resistant isolates of Enterobacteriaceae with MIC90 of 2 ug/ml; LYS228 is stable against Metallo-β-lactamases (MBLs), and shows small or no MIC shifts for most SBLs (serine β-lactamases), including CTX-Ms, KPCs and OXA-types.
Bacterial Infection
Phase 2 Clinical
| M.Wt | 518.472 | |
| Formula | C16H18N6O10S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Reck F, et al. Bioorg Med Chem Lett. 2018 Feb 15;28(4):748-755.
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