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Lacosamide

Chemical Structure : Lacosamide

CAS No.: 175481-36-4

Lacosamide (Erlosamide;SPM 927;ADD 234037)

Catalog No.: PC-61336Not For Human Use, Lab Use Only.

Lacosamide (SPM 927) is an anticonvulsant compound that enhances the slow inactivation of voltage-gated sodium channels without affecting the fast inactivation of voltage-gated sodium channels.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Lacosamide (SPM 927) is an anticonvulsant compound that enhances the slow inactivation of voltage-gated sodium channels without affecting the fast inactivation of voltage-gated sodium channels.
Lacosamide is launched for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain.

Physicochemical Properties

M.Wt 250.294
Formula C13H18N2O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2R)-2-(acetylamino)-N-benzyl-3-methoxypropanamide

References

1. Hao JX, et al. Eur J Pharmacol. 2006 Dec 28;553(1-3):135-40.

2. Lees G, et al. Neuropharmacology. 2006 Jan;50(1):98-110.

3. Duncan GE, et al. Epilepsy Res. 2005 Oct-Nov;67(1-2):81-7.

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