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Lamivudine

Chemical Structure : Lamivudine

CAS No.: 134678-17-4

Lamivudine (BCH-189, BCH189)

Catalog No.: PC-22321Not For Human Use, Lab Use Only.

Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI), inhibits HIV reverse transcriptase and also the reverse transcriptase of HBV, also inhibits long interspersed nuclear element-1 (LINE-1 or L1) reverse transcriptase.

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Biological Activity

Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI), inhibits HIV reverse transcriptase and also the reverse transcriptase of HBV, also inhibits long interspersed nuclear element-1 (LINE-1 or L1) reverse transcriptase.

Physicochemical Properties

M.Wt 229.25
Formula C8H11N3O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-Amino-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one

References

1. Colledge D, et al. Hepatology. 1997 Jul;26(1):216-25.

2. Jones, R. B. et al. PLoS One 3, 1–5 (2008).

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