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Chemical Structure : Laniquidar
Catalog No.: PC-70022Not For Human Use, Lab Use Only.
Laniquidar (R101933) is an orally active, third-generation P-glycoprotein inhibitor that inhibits the drug efflux pump P-glycoprotein, resulting in higher concentrations of antineoplastic agents in tumor cells that are multi-drug resistant due to the overexpression of P-glycoprotein.
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Laniquidar (R101933) is an orally active, third-generation P-glycoprotein (P-gp) inhibitor that inhibits the drug efflux pump P-glycoprotein, resulting in higher concentrations of antineoplastic agents in tumor cells that are multi-drug resistant due to the overexpression of P-glycoprotein.
| M.Wt | 584.7 | |
| Formula | C37H36N4O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. van Zuylen L, et al. Clin Cancer Res. 2000 Apr;6(4):1365-71.
2. van Zuylen L, et al. Eur J Cancer. 2002 May;38(8):1090-9.
3. Luurtsema G, et al. Nucl Med Biol. 2009 Aug;36(6):643-9.
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