Chemical Structure : Lck Inhibitor 25
Catalog No.: PC-42886Not For Human Use, Lab Use Only.
Lck Inhibitor 25 is a potent, selective Lck kinase inhibitor with IC50 of 7 nM, weakly inhibits Src and Lyn with IC50 of 42 and 21 nM, does not inhibits KDE and p38.
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Lck Inhibitor 25 is a potent, selective Lck kinase inhibitor with IC50 of 7 nM, weakly inhibits Src and Lyn with IC50 of 42 and 21 nM, does not inhibits KDE and p38.
Lck Inhibitor 25 inhibits T cell proliferation in vitro and inhibits arthritis in in vivo models.
M.Wt | 530.6229 | |
Formula | C31H30N8O | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Martin MW, et al. J Med Chem. 2008 Mar 27;51(6):1637-48.
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