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Chemical Structure : Lenacapavir
CAS No.: 2189684-44-2
Catalog No.: PC-35869Not For Human Use, Lab Use Only.
Lenacapavir (GS6207, GS-CA1) is a potent, selective inhibitor of HIV-1 capsid function, shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $188 | In stock | |
| 25 mg | $328 | In stock | |
| 50 mg | $528 | In stock | |
| 100 mg | Get quote |
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Lenacapavir (GS6207, GS-CA1) is a potent, selective inhibitor of HIV-1 capsid function, shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells.
Lenacapavir displays a mean EC50 of 50 pM (20-160 pM) against 23 HIV-1 clinical isolates from different subtypes in peripheral blood mononuclear cells (PBMCs).
Lenacapavir has potency and potential to be clinically effective against a broad range of HIV-1 strains.
| M.Wt | 968.28 | |
| Formula | C39H32ClF10N7O5S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(3bS,4aR)-N-[(1S)-1-[3-[4-Chloro-3-[(methylsulfonyl)amino]-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl]-6-[3-methyl-3-(methylsulfonyl)-1-butyn-1-yl]-2-pyridinyl]-2-(3,5-difluorophenyl)ethyl]-5,5-difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazole-1-acetamide |
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1. John O Link, et al. Nature. 2020 Jul 1.
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