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Chemical Structure : Lesinurad
CAS No.: 878672-00-5
Catalog No.: PC-20286Not For Human Use, Lab Use Only.
Lesinurad (RDEA594) is a potent selective urate anion transporter 1 (URAT1) inhibitor with IC50 of 3.5 and 81 µM for human and rat URAT1, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $58 | In stock | |
| 25 mg | $98 | In stock | |
| 50 mg | $158 | In stock | |
| 100 mg | $248 | In stock | |
| 250 mg | Get quote | ||
| 1 g | Get quote |
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Lesinurad (RDEA594) is a potent selective urate anion transporter 1 (URAT1) inhibitor with IC50 of 3.5 and 81 µM for human and rat URAT1, respectively.
Lesinurad (RDEA594) decreases uptake of urate by MDCK cells transfected with human URAT1.
Lesinurad (80 mg/kg) decreases serum levels of uric acid and urea nitrogen in a rat model of gout.
| M.Wt | 404.28 | |
| Formula | C17H14BrN3O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-[[5-bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic acid |
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1. Miner JN, et al. Arthritis Res Ther. 2016 Oct 3;18(1):214.
2. Dalbeth N, et al. Arthritis Rheumatol. 2017 Sep;69(9):1903-1913.
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