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Leucovorin

Chemical Structure : Leucovorin

CAS No.: 58-05-9

Leucovorin (Folinic acid)

Catalog No.: PC-26912Not For Human Use, Lab Use Only.

Leucovorin (folinic acid, calcium folinate) is a prescription form of reduced folic acid that does not require enzymatic activation by dihydrofolate reductase (DHFR), prevents side effects from certain medications, such as methotrexate.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Leucovorin (folinic acid, calcium folinate) is a prescription form of reduced folic acid that does not require enzymatic activation by dihydrofolate reductase (DHFR), prevents side effects from certain medications, such as methotrexate.

Physicochemical Properties

M.Wt 473.45
Formula C20H23N7O7
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(4-(((2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzoyl)-L-glutamic acid

References

1. Goldman ID, et al. NCI Monogr. 1987;(5):17-26.

2. Rosowsky A, et al. Biochem Pharmacol. 1989 Aug 15;38(16):2677-84.

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