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Chemical Structure : Leupeptin hemisulfate
CAS No.: 103476-89-7
Catalog No.: PC-45438Not For Human Use, Lab Use Only.
Leupeptin hemisulfate is a potent, reversible inhibitor of cysteine, serine, and threonine proteases, inhibits cathepsin B (Ki=6 nM), calpain (Ki=10 nM), trypsin (Ki=35 nM), plasmin (Ki=3.4 uM), and kallikrein (Ki=19 μM), and has no effect against chymotrypsin, elastase, renin, or pepsin.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $98 | In stock | |
| 10 mg | $158 | In stock | |
| 25 mg | $248 | In stock | |
| 100 mg | Get quote |
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Leupeptin hemisulfate is a potent, reversible inhibitor of cysteine, serine, and threonine proteases, inhibits cathepsin B (Ki=6 nM), calpain (Ki=10 nM), trypsin (Ki=35 nM), plasmin (Ki=3.4 uM), and kallikrein (Ki=19 μM), and has no effect against chymotrypsin, elastase, renin, or pepsin.
| M.Wt | 475.59 | |
| Formula | C20H38N6O4 . 1/2H2SO4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
H2O: ≥ 19 mg/mL |
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| Chemical Name/SMILES |
L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-formylbutyl]-, sulfate (2:1) |
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1. Berger DM, et al. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6519-23.
2. Mehdi S. Trends Biochem Sci. 1991 Apr;16(4):150-3.
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