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Linoleamide

Chemical Structure : Linoleamide

CAS No.: 3999-01-7

Linoleamide (Linoleic acid amide)

Catalog No.: PC-27044Not For Human Use, Lab Use Only.

Linoleamide is an endogenous lipid which is structurally related to sphingosine and sphiganine and closely related with sarco/endoplasmic reticulum Ca2+‐ATPase (SERCA) activity, increases cytosolic Ca2+ levels in MDCK with EC50 of 20 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Linoleamide is an endogenous lipid which is structurally related to sphingosine and sphiganine and closely related with sarco/endoplasmic reticulum Ca2+‐ATPase (SERCA) activity, increases cytosolic Ca2+ levels in MDCK with EC50 of 20 uM.
Linoleamide has been shown to induce sleep in cats, rats and humans.
Linoleamide inhibits Ca2+-ATPase activity of each SERCA with IC50 of 15-53 uM.

Physicochemical Properties

M.Wt 279.47
Formula C18H33NO
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(9Z,12Z)-octadeca-9,12-dienamide

References

1. J K Huang, et al. Life Sci. 2001 Jan 19;68(9):997-1004.

2. Sachiko Yamamoto, et al. Biochim Biophys Acta Gen Subj. 2017 Jan;1861(1 Pt A):3399-3405.

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