Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Linopirdine
CAS No.: 105431-72-9
Catalog No.: PC-63067Not For Human Use, Lab Use Only.
Linopirdine (DUP-996, Linopirine) is a potent Kv7 (KCNQ) voltage-gated potassium channels blocker.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $78 | In stock | |
| 10 mg | $118 | In stock | |
| 25 mg | $188 | In stock | |
| 50 mg | $298 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Linopirdine (DUP-996, Linopirine) is a potent Kv7 (KCNQ) voltage-gated potassium channels blocker.
Linopirdine blocks KV7.1+7.3 (KCNQ2+3)/M-currents (IC50=4-7 uM) and KV7.1 (KCNQ1) homomeric channels (IC50=8.9 uM).
Linopirdine inhibits M-type K+ current, increases acetylcholine release in rat hippocampal CA1 neurons; active in vivo.
| M.Wt | 391.465 | |
| Formula | C26H21N3O | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
1,3-Dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)-2H-indol-2-one |
|
1. Schnee ME, et al. J Pharmacol Exp Ther. 1998 Aug;286(2):709-17.
2. Wang HS, et al. Science. 1998 Dec 4;282(5395):1890-3.
3. Zaczek R, et al. J Pharmacol Exp Ther. 1998 May;285(2):724-30.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
