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Lisavanbulin dihydrochloride

Chemical Structure : Lisavanbulin dihydrochloride

CAS No.: 1387574-54-0

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Lisavanbulin dihydrochloride (BAL-101553 dihydrochloride)

Catalog No.: PC-23206Not For Human Use, Lab Use Only.

Lisavanbulin dihydrochloride (BAL101553) is a microtubule-destabilizing drug, binds to the colchicine site of tubulin, is the prodrug of the microtubule targeting agent Avanbulin (BAL27862).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Lisavanbulin dihydrochloride (BAL101553) is a microtubule-destabilizing drug, binds to the colchicine site of tubulin, is the prodrug of the microtubule targeting agent Avanbulin (BAL27862).

Physicochemical Properties

M.Wt 588.49
Formula C26H31Cl2N9O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(2S)-2,6-Diamino-N-[4-[2-[2-[4-[(2-cyanoethyl)amino]-1,2,5-oxadiazol-3-yl]-1H-benzimidazol-1-yl]acetyl]phenyl]hexanamide dihydrochloride

References

1. Prota AE, et al. J Mol Biol. 2014 Apr 17;426(8):1848-60.

2. Kolb EA, et al. Pediatr Blood Cancer. 2015 Jun;62(6):1106-9.

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