Livoletide (AZP-531) | GHSR agonist | Probechem Biochemicals

Chemical Structure : Livoletide

CAS No.: 1088543-62-7

Livoletide (AZP-531, AZP531)

Catalog No.: PC-61386Not For Human Use, Lab Use Only.

Livoletide (AZP-531) is the first-in-class analogue of unacylated ghrelin, and unacylated ghrelin receptor (GHS-R) agonist.

Packing	Price	Stock
5 mg	$298	In stock
10 mg	$458	In stock
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

Livoletide (AZP-531) is the first-in-class analogue of unacylated ghrelin, and unacylated ghrelin receptor (GHS-R) agonist.
Livoletide (AZP-531) exhibits the same pharmacological profile as UAG both in vitro and in vivo, independently of AG receptor binding.
Livoletide (AZP-531) prevents HFD-induced proinflammatory effects, stimulates expression of mitochondrial function markers in brown adipose tissue, and prevents development of a prediabetic metabolic state.
Livoletide (AZP-531) also prevents a HFD-induced increase in acyl ghrelin levels.

Physicochemical Properties

M.Wt	962.036
Formula	C40H63N15O13
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-((3S,6S,9S,12S,15S,18S,21S,26aS)-6-((1H-imidazol-4-yl)methyl)-9,18-bis(3-amino-3-oxopropyl)-12-(3-guanidinopropyl)-21-(hydroxymethyl)-15-isopropyl-1,4,7,10,13,16,19,22-octaoxohexacosahydropyrrolo[1,2-a][1,4,7,10,13,16,19,22]octaazacyclotetracosin-3-yl)propanoic acid

References

1. Julien M, et al. Eur J Pharm Sci. 2012 Nov 20;47(4):625-35.

2. Delhanty PJ, et al. FASEB J. 2013 Apr;27(4):1690-700.

3. Callaghan B, et al. Br J Pharmacol. 2014 Mar;171(5):1275-86.

4. Allas S, et al. Diabetes Obes Metab. 2016 Sep;18(9):868-74.

Livoletide (AZP-531, AZP531)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.