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Chemical Structure : Lixisenatide
CAS No.: 320367-13-3
Catalog No.: PC-47501Not For Human Use, Lab Use Only.
Lixisenatide (ZP10A) is a peptide glucagon-like peptide 1 (GLP-1) receptor agonist.
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| 10 mg | $298 | In stock | |
| 25 mg | $498 | In stock | |
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Lixisenatide (ZP10A) is a peptide glucagon-like peptide 1 (GLP-1) receptor agonist.
Lixisenatide (ZP10A) exhibits 4-fold higher affinity for the human GLP-1 receptor than GLP-1 (7-36) amide.
Lixisenatide (ZP10A) demonstrated dose-dependent improvement of glucose tolerance with an ED50 value of 0.02 nmol/kg i.p. in an oral glucose tolerance test (OGTT) in diabetic db/db mice.
| M.Wt | 4858.49 | |
| Formula | C215H347N61O65S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
H2O: 20 mM |
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| Chemical Name/SMILES |
His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Ser-Lys-Lys-Lys-Lys-Lys-Lys-NH2 |
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1. Umpierrez GE, et al. Diabetes Obes Metab. 2017 Mar 3.
2. Mezquita-Raya P, et al. Diabetes Ther. 2017 Apr;8(2):401-415.
3. Thorkildsen C, et al. J Pharmacol Exp Ther. 2003 Nov;307(2):490-6.
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