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Loperamide hydrochloride

Chemical Structure : Loperamide hydrochloride

CAS No.: 34552-83-5

Loperamide hydrochloride (R-18553 hydrochloride)

Catalog No.: PC-23788Not For Human Use, Lab Use Only.

Loperamide hydrochloride (R-18553) is a potent, selective mu-opioid receptor (MOR) agonist, also is a selective and competitive human intestinal carboxylesterases (hiCE) inhibitor, shows anti-diarrheal effect.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Loperamide hydrochloride (R-18553) is a potent, selective mu-opioid receptor (MOR) agonist, also is a selective and competitive human intestinal carboxylesterases (hiCE) inhibitor, shows anti-diarrheal effect.

Physicochemical Properties

M.Wt 513.50
Formula C29H34Cl2N2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-, hydrochloride (1:1)

References

1. Hanauer, S.B. Rev Gastroenterol Disord, 2008. 8(1): p. 15-20.

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