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Chemical Structure : Lopinavir
CAS No.: 192725-17-0
Catalog No.: PC-21700Not For Human Use, Lab Use Only.
Lopinavir (ABT-378) is a highly potent inhibitor of HIV-1 protease with Ki of 1.3 to 3.6 pM for wild-type and mutant HIV protease.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $88 | In stock | |
| 100 mg | $128 | In stock | |
| 200 mg | $188 | In stock | |
| 1 g | Get quote |
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Lopinavir (ABT-378) is a highly potent inhibitor of HIV-1 protease with Ki of 1.3 to 3.6 pM for wild-type and mutant HIV protease.
Lopinavir (ABT-378) blocks the replication of laboratory and clinical strains of HIV type 1 (50% effective concentration [EC50], 0.006 to 0.017 microM).
Lopinavir (ABT-378) maintains high potency against mutant HIV selected by ritonavir in vivo (EC50,
| M.Wt | 628.81 | |
| Formula | C37H48N4O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(S)-N-((2S,4S,5S)-5-(2-(2,6-Dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide |
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1. Sham HL, et al. Antimicrob Agents Chemother. 1998 Dec;42(12):3218-24.
2. Carrillo A, et al. J Virol. 1998 Sep;72(9):7532-41.
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