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Loratadine

Chemical Structure : Loratadine

CAS No.: 79794-75-5

Loratadine (Loratidine, SCH-29851)

Catalog No.: PC-45168Not For Human Use, Lab Use Only.

A tricyclic antihistamine that acts as a selective inverse agonist of peripheral histamine H1-receptors..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Loratadine is a tricyclic antihistamine that acts as a selective inverse agonist of peripheral histamine H1-receptors.

Physicochemical Properties

M.Wt 382.8832
Formula C22H23ClN2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester

References

1. Devillier P, et al. Clin Pharmacokinet. 2008;47(4):217-30.

2. Barnett A, et al. Agents Actions. 1984 Jun;14(5-6):590-7.

3. Roman IJ, et al. Clin Rev Allergy. 1993 Spring;11(1):89-110.

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