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Lotiglipron

Chemical Structure : Lotiglipron

CAS No.: 2401892-75-7

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Lotiglipron (PF-07081532, PF 07081532)

Catalog No.: PC-22331Not For Human Use, Lab Use Only.

Lotiglipron (PF-07081532) is an oral small-molecule glucagon-like peptide-1 receptor (GLP-1R) agonist, shows potential for type 2 diabetes (T2D) and/or obesity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Lotiglipron (PF-07081532) is an oral small-molecule glucagon-like peptide-1 receptor (GLP-1R) agonist, shows potential for type 2 diabetes (T2D) and/or obesity.

Physicochemical Properties

M.Wt 575.06
Formula C31H31ClN4O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-[[4-[(2S)-2-(5-Chloro-2-pyridinyl)-2-methyl-1,3-benzodioxol-4-yl]-1-piperidinyl]methyl]-1-[(2S)-2-oxetanylmethyl]-1H-benzimidazole-6-carboxylic acid

References

1. Clare Buckeridge, et al. Diabetes Obes Metab. 2024 May 16. doi: 10.1111/dom.15643.

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