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Chemical Structure : LpxC-IN-5
Catalog No.: PC-38420Not For Human Use, Lab Use Only.
LpxC-IN-5 is a potent non-hydroxamate LpxC (UDP-3-O-acyl-N-acetylglucosamine deacetylase) inhibitor with IC50 of 20 nM, shows antibacterial activity against E. coli ATCC25922, P. aeruginosa ATCC27853, K. pneumoniae ATCC13883 and P. aeruginosa 5567 with MIC of 16, 4, 64, and 4 ug/mL, respectively.
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LpxC-IN-5 is a potent non-hydroxamate LpxC (UDP-3-O-acyl-N-acetylglucosamine deacetylase) inhibitor with IC50 of 20 nM, shows antibacterial activity against E. coli ATCC25922, P. aeruginosa ATCC27853, K. pneumoniae ATCC13883 and P. aeruginosa 5567 with MIC of 16, 4, 64, and 4 ug/mL, respectively.
| M.Wt | 412.44 | |
| Formula | C21H24N4O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Yamada Y, et al. J Med Chem. 2020;10.1021/acs.jmedchem.0c01215.
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