Catalog No.: PC-25649Not For Human Use, Lab Use Only.
LpxH inhibitor AZ1 is the first reported inhibitor of LpxH with Ki of 53.4 nM for E. coli LpxH, shows MIC of 0.25 ug/mL against E. coli MG1655 ΔtolC, AZ1 inhibits 75% of the activity of K. pneumoniae LpxH at 1 uM.
LpxH inhibitor AZ1 is the first reported inhibitor of LpxH with Ki of 53.4 nM for E. coli LpxH, shows MIC of 0.25 ug/mL against E. coli MG1655 ΔtolC, AZ1 inhibits 75% of the activity of K. pneumoniae LpxH at 1 uM. LpxH catalyzes the fourth step in the synthesis of lipid A, the outer membrane anchor of lipopolysaccharide (LPS).
