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Lubeluzole

Chemical Structure : Lubeluzole

CAS No.: 144665-07-6

Lubeluzole

Catalog No.: PC-25065Not For Human Use, Lab Use Only.

Lubeluzole is a neuroprotective agent displaying antimyotonic activity, inhibits glutamate-stimulated guanosine 3',5'-cyclic monophosphate production with IC50 of 37 nM, inhibits the glutamate-activated nitric oxide synthase pathway.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Lubeluzole is a neuroprotective agent displaying antimyotonic activity, inhibits glutamate-stimulated guanosine 3',5'-cyclic monophosphate production with IC50 of 37 nM, inhibits the glutamate-activated nitric oxide synthase pathway.

Physicochemical Properties

M.Wt 433.52
Formula C22H25F2N3O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-1-(4-(benzo[d]thiazol-2-yl(methyl)amino)piperidin-1-yl)-3-(3,4-difluorophenoxy)propan-2-ol

References

1. Lesage AS, et al. J Pharmacol Exp Ther. 1996 Nov;279(2):759-66.

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