M1145

Chemical Structure : M1145

Catalog No.: PC-23336Not For Human Use, Lab Use Only.

M1145 is a chimeric peptide, potent, selective galanin receptor type 2 (GALR2) agonist with Ki of 6.55 nM, >50-fold selective over GALR1 (Ki=587 nM) and GALR3 (Ki=497 nM).

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Biological Activity

M1145 is a chimeric peptide, potent, selective galanin receptor type 2 (GALR2) agonist with Ki of 6.55 nM, >50-fold selective over GALR1 (Ki=587 nM) and GALR3 (Ki=497 nM).

Physicochemical Properties

M.Wt	2774.23
Formula	C128H205N37O32
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	L-Arginylglycyl-L-arginylglycyl-L-asparaginyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-valyl-L-leucyl-L-prolyl-L-prolyl-L-prolyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-alaninamide

References

1. Runesson J, et al. A novel GalR2-specific peptide agonist. Neuropeptides. 2009;43(3):187-192.

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M1145

Biological Activity

Physicochemical Properties

References

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