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M201-A

Chemical Structure : M201-A

CAS No.: 1868231-87-1

M201-A

Catalog No.: PC-22420Not For Human Use, Lab Use Only.

M201-A is a potent, selective ryanodine receptor 2 (RyR2) inhibitor, significantly reduces the diastolic Ca2+ in isolated rat ventricular cardiomyocytes, exhibits positive lusi-inotropic effects on rat heart.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

M201-A is a potent, selective ryanodine receptor 2 (RyR2) inhibitor, significantly reduces the diastolic Ca2+ in isolated rat ventricular cardiomyocytes, exhibits positive lusi-inotropic effects on rat heart.

Physicochemical Properties

M.Wt 440.60
Formula C25H32N2O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-4-[3-(4-benzylpiperidin-1-yl)propanoyl]-7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine-1-oxide

References

1. Noboru Kaneko, et al. Br J Pharmacol. 2024 May 21. doi: 10.1111/bph.16379.

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