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M2WJ-332

Chemical Structure : M2WJ-332

CAS No.: 1421958-72-6

M2WJ-332 (M2WJ 332)

Catalog No.: PC-70358Not For Human Use, Lab Use Only.

A potent inhibitor of drug-resistant S31N mutant of the M2 ion channel of influenza A virus with IC50 of 153 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A potent inhibitor of drug-resistant S31N mutant of the M2 ion channel of influenza A virus with IC50 of 153 nM; is more potent against S31N than amantadine against the WT M2.

Physicochemical Properties

M.Wt 314.447
Formula C18H22N2OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-(2-Thienyl)-N-tricyclo[3.3.1.13,7]dec-1-yl-3-isoxazolemethanamine

References

1. Wang J, et al. Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1315-20.

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