Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Antibiotics and Antivirals-Bacterial-M4284
M4284

Chemical Structure : M4284

CAS No.: 1373346-85-0

M4284 (M-4284, M 4284)

Catalog No.: PC-60900Not For Human Use, Lab Use Only.

M4284 (M-4284) is a high-affinity biphenyl mannoside FimH inhibitor with HAI of 16 nM in hemagglutination assay.

Packing Price Stock Quantity
5 mg $258 In stock
10 mg $398 In stock
25 mg $598 In stock
50 mg Get quote
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

M4284 (M-4284) is a high-affinity biphenyl mannoside FimH inhibitor with HAI of 16 nM in hemagglutination assay.
M4284 reduces intestinal colonization of genetically diverse UPEC isolates, while simultaneously treating UTI, without notably disrupting the structural configuration of the gut microbiota.
M4284 reduces UTI89 levels in the gut and urinary tracts of mice.

Physicochemical Properties

M.Wt 460.483
Formula C23H28N2O8
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N3,N5,3'-trimethyl-4'-(((3S,4R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-[1,1'-biphenyl]-3,5-dicarboxamide

References

1. Spaulding CN, et al. Nature. 2017 Jun 22;546(7659):528-532.

2. Jarvis C, et al. ChemMedChem. 2016 Feb 17;11(4):367-73.

3. Han Z, et al. J Med Chem. 2012 Apr 26;55(8):3945-59.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: