M4K2163 dihydrochloride

Chemical Structure : M4K2163 dihydrochloride

CAS No.: 2863635-04-3

Catalog No.: PC-26693Not For Human Use, Lab Use Only.

M4K2163 dihydrochloride is a potent, selective, blood-brain barrier (BBB) permeable activin receptor-like kinase-2 (ALK2) inhibitor with IC50 of 19 nM.

Packing	Price	Stock
5 mg	$98	In stock
10 mg	$148	In stock
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Biological Activity

M4K2163 dihydrochloride is a potent, selective, blood-brain barrier (BBB) permeable activin receptor-like kinase-2 (ALK2) inhibitor with IC50 of 19 nM.

Physicochemical Properties

M.Wt	480.41
Formula	C24H28Cl2FN3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-(5-(4-fluoro-3,5-dimethoxyphenyl)-4-methylpyridin-3-yl)phenyl)piperazine dihydrochloride

References

1. Smil D, et al. J Med Chem. 2020 Sep 10;63(17):10061-10085.

2. Rooney L, et al. ACS Omega. 2021 Aug 6;6(32):20729-20734.

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