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M7824

Chemical Structure : M7824

CAS No.:

M7824 (Anti-human PD-L1&TGF-β mAb, human IgG1-Kappa)

Catalog No.: PC-Ab1007Not For Human Use, Lab Use Only.

Bintrafusp alfa (M7824), a bifunctional fusion protein targeting TGF-β and PD-L1, attenuated features of TGF-β1-mediated mesenchymalization, including mesenchymal marker expression, proliferation suppression, and chemoresistance in vitro and in vivo..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Bintrafusp alfa (M7824), a bifunctional fusion protein targeting TGF-β and PD-L1, attenuated features of TGF-β1-mediated mesenchymalization, including mesenchymal marker expression, proliferation suppression, and chemoresistance in vitro and in vivo.

Physicochemical Properties

M.Wt
Formula Human IgG1-Kappa
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

References

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