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Chemical Structure : M8891
CAS No.: 1464842-09-8
Catalog No.: PC-73107Not For Human Use, Lab Use Only.
M8891 (M 8891) is an orally bioavailable, potent, and reversible methionine aminopeptidase 2 (MetAP2) inhibitor with IC50 of 54 nM, Ki of 4.33 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 2 mg | $328 | In stock | |
| 5 mg | $498 | In stock | |
| 10 mg | $788 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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M8891 (M 8891) is an orally bioavailable, potent, and reversible methionine aminopeptidase 2 (MetAP2) inhibitor with IC50 of 54 nM, Ki of 4.33 nM.
M8891 impede the growth of primary endothelial cells and demonstrated antitumoral activity in mouse models.
| M.Wt | 385.37 | |
| Formula | C20H17F2N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(S)-3-Hydroxy-1-(1H-indol-5-yl)-2-oxo-pyrrolidine-3-carboxylic Acid 3,5-Difluoro-benzylamide |
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1. Heinrich T, et al. J Med Chem. 2019 Dec 26;62(24):11119-11134.
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