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Chemical Structure : MAC13772
CAS No.: 4871-40-3
Catalog No.: PC-20744Not For Human Use, Lab Use Only.
MAC13772 is a small molecule inhibitor of bacterial enzyme BioA with IC50 of 250 nM, the antepenultimate step in biotin biosynthesis, MAC13772 inhibits biotin biosynthesis.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $88 | In stock | |
| 25 mg | $138 | In stock | |
| 50 mg | $228 | In stock | |
| 100 mg | Get quote |
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MAC13772 is a small molecule inhibitor of bacterial enzyme BioA with IC50 of 250 nM, the antepenultimate step in biotin biosynthesis, MAC13772 inhibits biotin biosynthesis.
MAC13772 is effective against antibiotic-resistant pathogens.
MAC13772 is capable of dampening the viability of carbapenem-resistant P. aeruginosa (CRPA).
MAC13772 interferes the production of pyocyanin, an important virulence factor of P. aeruginosa.
| M.Wt | 227.24 | |
| Formula | C8H9N3O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-((2-nitrophenyl)thio)acetohydrazide |
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1. Zlitni S, et al. Nat Chem Biol. 2013 Dec;9(12):796-804.
2. Carfrae LA, et al. Nat Microbiol. 2020 Jan;5(1):93-101.
3. Shi Y, et al. PLoS Pathog. 2023 Jan 23;19(1):e1011110.
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