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MALT1 inhibitor 8

Chemical Structure : MALT1 inhibitor 8

CAS No.: 2866252-67-5

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MALT1 inhibitor 8

Catalog No.: PC-49479Not For Human Use, Lab Use Only.

MALT1 inhibitor 8 is a potent, selective and orally bioavailable MALT1 inhibitor with cellular IC50 of 3.2 uM, binds to an induced allosteric site in MALT1.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    MALT1 inhibitor 8 is a potent, selective and orally bioavailable MALT1 inhibitor with cellular IC50 of 3.2 uM, binds to an induced allosteric site in MALT1.

    Physicochemical Properties

    M.Wt 412.805
    Formula C16H16ClF3N8
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (1s,4s)-N1-(3-chloro-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-N4-(2-(trifluoromethyl)pyrimidin-4-yl)cyclohexane-1,4-diamine

    References

    1. Stefan Schiesser, et al. Eur J Med Chem. 2022 Jan 5;227:113925.

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