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MALT1 inhibitor 8

Chemical Structure : MALT1 inhibitor 8

CAS No.: 2866252-67-5

MALT1 inhibitor 8

Catalog No.: PC-49479Not For Human Use, Lab Use Only.

MALT1 inhibitor 8 is a potent, selective and orally bioavailable MALT1 inhibitor with cellular IC50 of 3.2 uM, binds to an induced allosteric site in MALT1.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MALT1 inhibitor 8 is a potent, selective and orally bioavailable MALT1 inhibitor with cellular IC50 of 3.2 uM, binds to an induced allosteric site in MALT1.

Physicochemical Properties

M.Wt 412.805
Formula C16H16ClF3N8
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(1s,4s)-N1-(3-chloro-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-N4-(2-(trifluoromethyl)pyrimidin-4-yl)cyclohexane-1,4-diamine

References

1. Stefan Schiesser, et al. Eur J Med Chem. 2022 Jan 5;227:113925.

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