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Chemical Structure : MAO-B inhibitor 8f
Catalog No.: PC-61487Not For Human Use, Lab Use Only.
MAO-B inhibitor 8f is a potent, selective monoamine oxidase B (MAO-B) inhibitor with IC50 of 29-56 nM.
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MAO-B inhibitor 8f is a potent, selective monoamine oxidase B (MAO-B) inhibitor with IC50 of 29-56 nM.
MAO-B inhibitor 8f shows no significant activity over MAO-A (>10 uM).
MAO-B inhibitor 8f shows improvement for memory in multiple animal models, has an excellent profile against a panel of other enzymes and receptors, good pharmacokinetic properties in rodents and dogs.
| M.Wt | 359.367 | |
| Formula | C15H16F3N3O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kaplan A, et al. ACS Chem Neurosci. 2017 Dec 20;8(12):2746-2758.
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