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MAP4K4-IN-17

Chemical Structure : MAP4K4-IN-17

CAS No.: 1811510-58-3

MAP4K4-IN-17

Catalog No.: PC-62935Not For Human Use, Lab Use Only.

MAP4K4-IN-17 is a potent and highly selective MAP4K4 inhibitor with IC50 of 14.9 nM, showes improved overall drug-like properties compared to PF-06260933.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MAP4K4-IN-17 is a potent and highly selective MAP4K4 inhibitor with IC50 of 14.9 nM, showes improved overall drug-like properties compared to PF-06260933.
MAP4K4-IN-17 is a lead compound for advanced preclinical development.

Physicochemical Properties

M.Wt 297.746
Formula C15H12ClN5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-(6-amino-5-(4-chlorophenyl)pyridin-3-yl)pyrimidin-2-amine

References

1. Ammirati M, et al. ACS Med Chem Lett. 2015 Oct 6;6(11):1128-33.

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