MAP4K4-IN-17 |CAS:1811510-58-3 Probechem Biochemicals

Chemical Structure : MAP4K4-IN-17

CAS No.: 1811510-58-3

MAP4K4-IN-17

Catalog No.: PC-62935Not For Human Use, Lab Use Only.

MAP4K4-IN-17 is a potent and highly selective MAP4K4 inhibitor with IC50 of 14.9 nM, showes improved overall drug-like properties compared to PF-06260933.

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10 mg	$78	In stock
25 mg	$138	In stock
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Biological Activity

MAP4K4-IN-17 is a potent and highly selective MAP4K4 inhibitor with IC50 of 14.9 nM, showes improved overall drug-like properties compared to PF-06260933.
MAP4K4-IN-17 is a lead compound for advanced preclinical development.

Physicochemical Properties

M.Wt	297.746
Formula	C15H12ClN5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(6-amino-5-(4-chlorophenyl)pyridin-3-yl)pyrimidin-2-amine

References

1. Ammirati M, et al. ACS Med Chem Lett. 2015 Oct 6;6(11):1128-33.

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MAP4K4-IN-17

Biological Activity

Physicochemical Properties

References

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